[Molecular mechanisms leading to spinal motoneurons specialization in vertebrates].

نویسندگان

  • Sophie Chauvet
  • Eric Dessaud
  • Odile de Lapeyrière
چکیده

Note : les règles d'écriture des références bibliographiques peuvent varier selon les différents domaines du savoir. Ce document est protégé par la loi sur le droit d'auteur. L'utilisation des services d'Érudit (y compris la reproduction) est assujettie à sa politique d'utilisation que vous pouvez consulter à l'URI

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Nicotinomid Adenin Dinucleotide Phosphate-Diaphorase (NADPH-d) Activity and CB-28 kDa Immunoreactivity in Spinal Neurons of Neonatal Rats after a Peripheral Nerve Lesion

Our previous studies have shown that median and ulnar nerve lesion induced calbindin (CB) immunoreactivity in some injured motoneurons in developing rats. Motoneuron death induced by sciatic nerve transection in neonatal rats has been related to induction of neuronal isoform of nitric oxide synthase (nNOS). The present study investigated whether expression of CB and nicotinomid adenin dinucleot...

متن کامل

بررسی تغییرات فاکتور نروتروفیکی BDNF و گیرنده‌های آن (P75, TrK-B) پس از قطع عصب سیاتیک در نوزاد موش صحرایی

  Background & Objective : As apoptotic cell death plays an important role in natural development and many pathologic conditions such as cancer and neurodegenerative diseases, understanding of its molecular mechanisms can be useful in designing new therapeutic strategies. In present study following induction of apoptosis in spinal motoneurons, expression of neurotrophic factor BDNF, and its rec...

متن کامل

Time Course of Axotomy-induced Changes in Synaptophysin Pattern and Synaptic Reaction of Spinal Motoneurons in Adult Rat

Background and Objective: Evaluation of degenerative changes of motoneurons and their related synapses can be useful in understanding the mechanisms of neurodegenerative diseases and their potential treatment. The present electron microscopic and immunohistochemical study investigates the axotomy-induced...

متن کامل

Formation of specific monosynaptic connections between muscle spindle afferents and motoneurons in the mouse.

In adult vertebrates, sensory neurons innervating stretch-sensitive muscle spindles make monosynaptic excitatory connections with specific subsets of motoneurons in the spinal cord. Spindle afferents (Ia fibers) make the strongest connections with motoneurons supplying the same (homonymous) muscle but make few or no connections with motoneurons supplying antagonistic or functionally unrelated m...

متن کامل

Delayed Synaptic Changes in Axotomized Spinal Motoneurons of Newborn Rats Associated with Progressive Neuronal Loss: Immunohistochemical, Ultrastructural, and Quantitative Study

Background and Objective: Sciatic nerve transection is characterized by a rapid wave of motoneuron death associated with progressive synaptic lesions. The purpose of this study was to evaluate the long term synaptic changes. Materials and Methods: This basic study was carried out on paraffin- or resin-em...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Medecine sciences : M/S

دوره 20 2  شماره 

صفحات  -

تاریخ انتشار 2004